Pharma Biochemist
This role will specialize in protein purification, complex stabilization, cryo-EM sample preparation, and rigorous QC to deliver high-quality, structurally relevant samples for analysis.
Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to support the life sciences industry by cultivating and empowering exceptional scientists to deliver specialized laboratory services that advance research, foster collaboration, and accelerate innovation through quality and a shared commitment to excellence. We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.
Cogent Scientific offers competitive pay, attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment. This position may include relocation benefits as well. We aim to recruit the best people who stand out among their peers and embody our Core Values:
Client Focused: We only succeed when our clients succeed.
Outstanding: We deliver meticulous results through outstanding performance.
Good: We act ethically and morally.
Employee-Centric: We honor and support our employees.
Nimble: We are prepared to adapt in an ever-changing industry.
Team-Oriented: We collaborate with each other and with our clients.
We currently have a role available for a Pharma Biochemist.
Job duties include, but are not limited to, the following:
Designing, executing and testing protein purification workflows, including conditions tailored to fragile complexes or samples with significant structural flexibility
Performing multi-step chromatography (affinity, ion exchange, size-exclusion) to achieve high-purity, monodisperse protein/complex samples
Optimizing buffer conditions and sample stability for cryo-EM grid preparation
Preparing and screening cryo-EM grids; evaluating particle distribution and ice quality
Performing QC assays (SDS-PAGE, DLS, mass photometry, negative-stain EM) to assess sample homogeneity prior to data collection
Maintaining detailed records of protocols, results, and sample provenance
Performing other related duties as assigned.
Job requirements include, but are not limited to, the following:
BS - Biochemistry, Biophysics, Structural Biology, Chemistry, or Biology, with prior laboratory experience (at least 2 years) involving protein handling, biochemistry, and purification.
Familiarity with protein quality assessment or characterization techniques (e.g., SDS-PAGE, ÄKTA, HPLC, SEC, UV spectroscopy).
Experience in structural biology or cryo-EM is preferred, but not required.
Strong organizational skills and impeccable verbal and written communication skills.
Advanced proficiency with Microsoft Office Suite.
Excellent attention to detail.
Ability to work well both independently and within a team.
Very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.
The ideal candidate should be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.
This is an onsite, day shift position (approx. 8a-5p local time).
Cogent Scientific provides equal employment opportunities to all applicants and does not discriminate based on any legally protected characteristic.
Additionally, if you require a reasonable accommodation during the application or interview process, please let us know.
This job posting will close by 12/31/2026 or when a candidate is identified, whichever comes first.
- Department
- Scientific Services
- Role
- Biochemist
- Location
- La Jolla - Campus Point Dr.
- Salary
- $70,000 - $75,000/year
- Employment type
- Full-time
About Cogent Scientific
The pharmaceutical and biotech industries experienced a tremendous amount of change this past decade. For companies to remain relevant and competitive, they must respond quickly and effectively to the unique challenges they face. Our company was started to assist companies in navigating these hurdles.
Cogent has earned a reputation for reliability regarding our partnership to our clients. We believe that the key to maintaining that commitment is attracting and retaining good people to be a part of our team. Our commitment to our clients is intertwined with our commitment to our employees.
Cogent employs talented individuals who also bring a positive, team oriented approach to the tasks at hand. Each day, our people demonstrate their motivation and initiative to make things simple and to innovate while being empowered by the drive to make the right decisions.
This passion for excellence means our customers trust our partnership and employees choose to join – and stay with – Cogent Scientific.